Dr Simon Bailey
Staff Profile:
Dr Simon R. Bailey BVMS PhD FHEA DipECVPT MRCVS
Senior Lecturer in Pre-Clinical Veterinary Sciences
After two years in mixed practice, Dr Bailey undertook a PhD at the Royal Veterinary College, London, in veterinary pharmacology, studying equine laminitis. He then continued in post-doctoral research at the RVC for 4 years working in the fields of laminitis, endotoxaemia and inflammation.
From 2002-2004, Dr Bailey worked as a research scientist at the Dorothy Davis Heart and Lung Research Institute at the Ohio State University Medical Center, Columbus, Ohio, where he undertook research in vascular biology with relevance to peripheral vascular disease in man. He then returned to London to take up a lectureship in the Veterinary Basic Sciences Department at the Royal Veterinary College.
Dr Bailey moved to the University of Melbourne as a lecturer in Pre-clinical Veterinary Sciences in March 2007.
Contact details:
Telephone: +613 8344 6315
Facsimile: +613 8344 7374
Email form: click to contact
Appointments:
Lecturer in Pre-Clinical Veterinary Sciences
Associate Dean – students (Parkville)
Teaching Responsibilities:
250-105 Veterinary Professional Studies
250-108,109 Veterinary Anatomy 1A,B
250-116,117 Veterinary Physiology 1A,B
250-204 Veterinary Physiology 2
Field of Expertise:
Veterinary Pharmacology and Pre-Clinical Sciences
Research Interests:
Equine laminitis
Equine endotoxaemia
Vascular biology
Veterinary Pharmacology
Current Research Projects:
Risk factors for equine laminitis in ponies
Hindgut-derived trigger factors for acute laminitis
Effects of endotoxin on blood vessels
The effects of cooling on the cutaneous microvasculature
Selected Publications:
Bailey, S.R., Habershon-Butcher, J.L., Ransom, K.J, Elliott, J. and Menzies-Gow, N.J. (2007). Hypertension and insulin resistance in a mixed-breed population of ponies predisposed to laminitis: Further characterizing pre-laminitic metabolic syndrome. American Journal of Veterinary Research (In press).
Bailey, S.R., Menzies-Gow, N.J., Harris, P.A., Habershon-Butcher, J.L., Crawford, C., Berhane, Y., Boston, R.C. and Elliott, J. (2007). Dietary fructans and glucocorticoids produce exaggerated insulin responses in ponies predisposed to laminitis. Journal of the American Veterinary Medical Association (In press).
Zerpa, H., Berhane, Y., Elliott, J. and Bailey, S.R. (2007). Cooling augments vasoconstriction mediated by 5-HT1 and 2-adrenoceptors in the isolated equine digital vein: involvement of Rho kinase. European Journal of Pharmacology (In press).
Menzies-Gow, N.J., Sepulveda, M.F., Bailey, S.R., Cunningham F.M. and Elliott, J. (2007). Thromboxane A2 and 5-hydroxytryptamine mediate endotoxin-induced digital vasoconstriction in horses. American Journal of Veterinary Research (In press).
Brooks, A.C., Menzies-Gow, N.M.J., Wheeler-Jones C., Bailey, S.R., Cunningham, F.M. and Elliott, J. (2007). Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production. Inflammation Research 56(4): 154-161.
Bailey, S.R., Mitra, S, Flavahan. S., Bergdall, V.K. and Flavahan, N.A. (2007). In vivo endothelial denudation disrupts smooth muscle caveolae and differentially impairs agonist-induced constriction in small arteries. Journal of Cardiovascular Pharmacology 49:183-90.
Bailey, S.R. and Elliott, J. (2007). The corticosteroid laminitis story: Science of if, when and how. Equine Veterinary Journal 39 (1): 7-11.
Harris, P., Bailey, S.R., Elliott, J. and Longland, A. (2006). Countermeasures for pasture associated laminitis in ponies and horses. Journal of Nutrition 136: 2114S-2121S
Bailey SR, Mitra S, Flavahan S and Flavahan NA. (2005). Reactive oxygen species from smooth muscle mitochondria initiate cold-induced constriction of cutaneous arteries. American Journal of Physiology (Heart and Circulation Physiology) 289(1):H243-50
Menzies-Gow, N., Bailey, S.R., Stevens, K., Katz, L.M., Marr, C.M., and Elliott, J. (2005). Digital blood flow and plasma endothelin concentration in clinically endotoxemic horses. American Journal of Veterinary Research 66 (4): 630-6.
Flavahan, N.A., Bailey, S.R., Flavahan, W.A., Mitra, S. and Flavahan, S. (2005). Imaging remodelling of the actin cytoskeleton in vascular smooth muscle cells following mechanosensitive arteriolar constriction. American Journal of Physiology (Heart and Circulation Physiology) 288: H660-H669.
Bailey, S.R. Eid, A.H., Mitra, S., and Flavahan, N.A. (2004). The Rho /Rho kinase pathway mediates cold-induced contractility in cutaneous arteries. Circulation Research 94: 1367-1374.
Bailey, S.R., Marr, C.M., and Elliott, J. (2004). Review: Current research and theories on the pathogenesis of acute laminitis in the horse. The Veterinary Journal 167 (2):129-42.
Bailey, S.R., Cunningham, F.M., (2001). Adherence of eosinophils from allergic and normal ponies to cultured equine endothelial cells. Inflammation Research 50, 32-38.
Further Publications: PubMed Search